Inuyasha, Dragon Ball, Rurouni Kenshin, Yu Yu Hakusho, Trinity Blood, Trigun...and most importantly, Wolf's Rain! It has been my favorite anime since it first broke my heart. </3 I even cosplay Blue!
I'd have to say Howl's Moving Castle is my fav, since that's the one I keep going back to and watching the most! That and I love an underdog story and Sophie is a great underdog!