I don't mean the best puzzle game, I mean a puzzle game that really forces you to think creatively.
I'm going to say Antichamber. It's so abstract and confusing, especially with the perception-based puzzles. And the dev rooms give it a little bit of replayability as well.
now listen here you little shit
ok but seriously, the fandom is like every other fandom in its terribility, but from your description of Homestuck, it seems like you haven't given it a big enough chance. It's something that requires a commitment, and a lot of patience. In the later acts, it's...