Hey there!
I love angst too, and I'm interested in some of the pairings you've mentioned (maybe we can build on those to turn up the angst factor?), like the co-workers, friends to enemies to lovers (chef's kiss), college, childhood friends to strangers to lovers, and the detective/civilian...
As someone whose recent RP craving (almost) has been Superhero x Supervillain, I'd love to chat with you about your hero/villain idea. :')
I'm also looking for a long-term literate partner, so this is right up my alley.~